Justin Bieber and Selena Gomez have broken up, reports say
















LOS ANGELES (Reuters) – Pop star Justin Bieber and his girlfriend, Selena Gomez, a Disney actress and singer, have broken up, ending a relationship that made them one of Hollywood’s most high-profile young couples, media reports said.


Bieber, 18, and Gomez, 20, disclosed their relationship in February 2011 when they appeared together at an Oscar night party after months of rumors of their dating.













E! Online late on Friday was the first to report the split, with other media outlets including US Weekly and People also saying the relationship was over. The reports cited unnamed sources close to the couple.


Representatives for Bieber and Gomez did not returns calls or emails on Saturday.


Bieber has released two No. 1 albums in just over a year – the holiday-themed “Under the Mistletoe” and his latest, “Believe.” In September, he topped Billboard’s “21 Under 21″ list of top young musical acts. It was his second year in a row with the title.


Gomez rose to fame as a teenager in the Walt Disney Co television series “Wizards of Waverly Place” and has enjoyed success as a pop singer.


(Reporting By Alex Dobuzinskis; Editing by Greg McCune and Peter Cooney)


Celebrity News Headlines – Yahoo! News



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Boehringer Ingelheim to start late-stage hepatitis C drug trial
















BOSTON (Reuters) – Boehringer Ingelheim said on Saturday it plans to initiate a late-stage clinical trial of its experimental hepatitis C treatment following promising results from earlier studies.


The company announced final data from a mid-stage trial of its treatment regimen which showed that 69 percent of patients in the study were free of the virus 12 and 24 weeks following the end of treatment.













Hepatitis C is a blood-borne infectious disease of the liver that can lead to liver failure and transplant.


Historically, hepatitis C has been treated with pegylated interferon and ribavirin, but treatment lasts as long as 48 weeks and interferon is associated with flu-like side effects.


The goal of drugmakers now, including Boehringer, Vertex Pharmaceuticals Inc, Gilead Sciences Inc and Bristol-Myers Squibb Co is to develop products that do not need to be combined with interferon. Most analysts consider Gilead to currently be at the forefront of the race.


Full results from Boehringer’s trial, known as SOUND-C2, were presented at the annual meeting of the American Association for the Study of Liver Diseases in Boston. Preliminary data were presented earlier this year.


Boehringer’s trial tested a combination of BI-201335, a protease inhibitor, BI-207127, a polymerase inhibitor, and ribivirin.


Boehringer is a privately held company headquartered in Ingelheim, Germany.


(Reporting By Toni Clarke; Editing by Marguerita Choy)


Health News Headlines – Yahoo! News



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Boehringer Ingelheim to start late-stage hepatitis C drug trial
















BOSTON (Reuters) – Boehringer Ingelheim said on Saturday it plans to initiate a late-stage clinical trial of its experimental hepatitis C treatment following promising results from earlier studies.


The company announced final data from a mid-stage trial of its treatment regimen which showed that 69 percent of patients in the study were free of the virus 12 and 24 weeks following the end of treatment.













Hepatitis C is a blood-borne infectious disease of the liver that can lead to liver failure and transplant.


Historically, hepatitis C has been treated with pegylated interferon and ribavirin, but treatment lasts as long as 48 weeks and interferon is associated with flu-like side effects.


The goal of drugmakers now, including Boehringer, Vertex Pharmaceuticals Inc, Gilead Sciences Inc and Bristol-Myers Squibb Co is to develop products that do not need to be combined with interferon. Most analysts consider Gilead to currently be at the forefront of the race.


Full results from Boehringer’s trial, known as SOUND-C2, were presented at the annual meeting of the American Association for the Study of Liver Diseases in Boston. Preliminary data were presented earlier this year.


Boehringer’s trial tested a combination of BI-201335, a protease inhibitor, BI-207127, a polymerase inhibitor, and ribivirin.


Boehringer is a privately held company headquartered in Ingelheim, Germany.


(Reporting By Toni Clarke; Editing by Marguerita Choy)


Health News Headlines – Yahoo! News



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The Workday After Tomorrow
















What happens when business as usual is impossible? When millions in the Northeast lost power, cell service, Internet access, and running water due to Superstorm Sandy, companies scrambled to find the answer. Some improvised on the spot: Keith McNally’s New York City bistro Balthazar grilled steaks and served lobster on Prince Street, while Katz’s Delicatessen sliced up sandwiches by candlelight. Manhattan’s Equinox fitness clubs started a second business, selling showers for $ 35 a pop. Large financial firms such as Goldman Sachs (GS) began relocating staff and workloads from New York to offices overseas, and tens of thousands of workers turned to the cloud, working from home—or Starbucks (SBUX). Meanwhile, Tim Webster, a customer enablement manager at EMaint Enterprises, an info-tech company in Mount Laurel, N.J., found himself in a Florida Wal-Mart (WMT), picking out a Captain America costume for the company’s impromptu Halloween party. “It’s hard to complain,” he says. “I mean, it’s a bit cold this morning. Maybe you need a light jacket?”


Webster was one of five employees flown down to EMaint’s satellite office in Estero, Fla., on the Saturday before Sandy hit, as part of the company’s business continuity plan. “It looked like we were going to get battered here in South Jersey, with mass power outages and trees down, and we have customers worldwide,” says Jon Hollander, executive vice president of operations. “So we decided to send five of our core-function employees for an expense-paid vacation in sunny Florida.”













Thanks to data stored in the cloud, the company was able to provide service to its clients without interruption. But Webster (who insists “it’s not a vacation—I’m still working”) is still playing it safe. “I’m staying out of the sun,” he says, noting how weird it’s been to see his colleagues wearing shorts.


093af  etc opener46  01  inline405 The Workday After TomorrowIllustration by Marcos Chin


World economic losses to disasters totaled an estimated $ 380 billion in 2011, and nearly every major company now sets up detailed continuity and mitigation plans for everything from terrorist incidents and nuclear attacks to pandemics like bird flu. A cottage industry of in-house sky-is-falling professionals and glass-half-empty consulting firms has sprung up to deal with this need. And as companies become more reliant on digital data and geographically diverse locations, their strategies must evolve, too. “For instance, people don’t warehouse parts anymore,” says Ken Burris, chief executive officer of Witt Associates, a crisis management consultancy. “They rely on just-in-time delivery. But when there’s that hiccup in the supply chain, they’d better have multiple contingencies in place, or work stops.” And Burris points out that the implications are often dire: “Statistics show that, of small businesses impacted by disaster, about a third don’t recover.”


The biggest difference between recent disruptions and those only a decade ago shows up in businesses’ increasing faith in cloud computing, which was sorely tested by Sandy. As Lower Manhattan was swamped, major media companies such as Huffington Post, MarketWatch, and Gawker saw their sites go offline as water flooded the basement floors of the Datagram server building. Gawker Media eventually improvised by redirecting Gawker, Gizmodo, and Deadspin to temporary Tumblr blog pages. “If we’re the indestructible cockroaches of the media world,” Gawker founder Nick Denton e-mailed his staff, “now’s the time to show it.” Still, the network lost nearly all its advertising opportunities, save a cheeky “Back Up Site Covered by State Farm” plug at the top of each site’s Tumblr home page.


Peer1 Hosting, a Net outfit based in Lower Manhattan, thought it was in the clear—it had generators on the 17th floor ready to keep the data servers humming. But when the fuel pump in the basement was flooded, Peer1 was unable to get the necessary diesel fuel upstairs. So it improvised, too. “We had a team of 30 people getting buckets of diesel fuel going up 17 floors to keep the generator working and our customers online,” says Rajan Sodhi, Peer1’s vice president of marketing. Employees hoofed it up darkened stairwells for more than 48 hours, replenishing the tanks.


Shawn White, vice president of operations for Keynote Systems, which monitors online access, says many companies have turned to the cloud primarily for cost savings, not safety. “If you’re going to be in the cloud, you have to make sure they have options for multiple data centers in a geographically distributed base. It’s extra money, but that’s the cost of a robust continuity plan,” he says.


And obviously the cloud can’t help if you don’t have electricity, cell service, or Net access. In the 10 states hit by Sandy, 25 percent of cell towers and land lines were affected by the storm, according to the Federal Communications Commission. Downtown New York lost power for nearly a week. “People keep asking what they can do if there is absolutely no power at all, anywhere,” says Ken Moon, co-founder of Connecticut-based emergency software platform Veoci Systems. “I say, ‘It’s smoke signals and CBs, if you got ’em. And how long the juice lasts on your cell phone, if your cell phone works.’”


093af  etc opener46 4051 The Workday After TomorrowClick to enlarge


Throughout the Northeast, many of the contingency plans at businesses failed, most notably at several hospitals, which were left without working backup generators and forced to evacuate patients. Now experts are sorting out why. “This notion that big disasters are wake-up calls?” Irwin Redlener, director of the National Center for Disaster Preparedness, asks. “They’re more like snooze alarms. Everyone gets aroused, then we end up repeating mistakes. For too long we’ve depended upon seat-of-the-pants decision-making to determine disaster policy. We have a lot of data about what actually works.”


So how does a company or government stress the importance of disaster planning when a storm isn’t bearing down? By invoking the undead, of course. “Are You Zombie Safe?” asks a Red Cross video promoting its disaster preparedness training program. The Centers for Disease Control and Prevention published a graphic novel, Preparedness 101: Zombie Pandemic. The Federal Emergency Management Agency and the Department of Homeland Security also have so-called zombie-based safety programs. In fact, while the East Coast scrambled to recover from Sandy, thousands of first responders and security firms were preparing for Zombie Apocalypse, an emergency-response training event held at the Paradise Point Resort in San Diego.


“We get all these first responders in here and tell them the sky is falling, the Mayans were right, the clock is ticking, and your bosses are watching,” says Brad Barker, president and founder of Halo, the event’s organizer. In addition to simulating crisis-driven hysteria, he also dresses up actors as zombies in elaborate Hollywood makeup and orders them to eat the humans’ brains. “We got our asses handed to us during Katrina on live TV, and everyone knows it,” says Barker. “We create hyper-realistic training, so you can put together a plan for a mass casualty event of any kind, whether that’s seismic, meteorological, biological, or somebody flies a couple planes into your building. The zombies just make it fun.”


But what happens when every plan has fallen apart and it’s just you, your cubicle, and a horde of alien, radioactive, bird-flu-infected terrorist zombies? “The priorities of survival are always the same, whatever the terrain or disaster,” says Bear Grylls, celebrity survivalist and host of TV show Man vs. Wild. “Protection, rescue, water, food.” Grylls recommends gathering office trash bags and using them for shelter, water collection, or waterproofing your tinder and cell phone. “Remember, you can only last three days without water, but three weeks without food.” On that last note, Grylls says that even in an office environment (the filthier the better), would-be survivalists should look for “bugs, grubs, and worms before rats or bigger game—as well as the obvious, like vending machines and cans.”


Last (and, yes, least), take a page from such fictional companies as Cyberdyne Systems in the Terminator franchise, Weyland Yatuni in Alien, BuyNLarge in Wall-E, and the Trade Federation of the Star Wars prequels. They’re all extraordinarily evil. So evil, in fact, that in most post-apocalyptic fiction, the company last left standing is usually the one that created the catastrophic calamity in the first place. If the collected wisdom of sci-fi is right, a company’s best long-term disaster preparedness strategy is the opposite of Google’s (GOOG): Be Evil.


Businessweek.com — Top News



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Twin explosions strike southern Syrian city
















BEIRUT (AP) — Syria‘s state-run news agency says two large explosions have struck the southern city of Daraa, causing multiple casualties and heavy material damage.


SANA did not immediately give further information or say what the target of Saturday’s explosions was.













The Britain-based Syrian Observatory for Human Rights says the blasts went off near a branch of the country’s Military Intelligence in Daraa.


The Observatory, which relies on a network of activists on the ground, says the explosions were followed by clashes between regime forces and rebels fighting to topple President Bashar Assad.


Middle East News Headlines – Yahoo! News



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Ohio teen gets prison for life in Craigslist murders
















AKRON, Ohio (Reuters) – Seventeen-year-old Brogan Rafferty was sentenced to life in prison without parole Friday for his role in the killing of three men, two of whom were lured by a Craigslist ad promising work on an Ohio farm.


Rafferty was 16 when he was arrested in November 2011, but was tried as an adult. He was convicted late last month in the murders of David Pauley, 51, of Norfolk, Virginia; Ralph Geiger, 56, of Akron, Ohio; and Timothy Kern, 47, of Massillon, Ohio.













Rafferty also got 10 years for the attempted murder of Scott Davis, who was shot in the arm while escaping after meeting Rafferty and alleged triggerman Richard Beasley.


Prosecutors called the teen an apt pupil to Beasley, 53, who is also charged in the murders.


Rafferty testified that he was terrified of the man he had considered a father figure and spiritual adviser after he saw Beasley shoot Geiger in the head execution-style.


Beasley allegedly enticed Geiger with the offer of a non-existent caretaker job, killed him, stole his identity, and then drew other victims by posting the bogus job on Craigslist.


Rafferty, wearing prison stripes with hands clasped in front of him, told the court Friday that Beasley an “evil, deceitful cruel murderer,” but admitted the he bore some responsibility.


“I was involved, I didn’t like it, and now I see there were many options I couldn’t see then that I see now, but I can’t make anything better and I’m sorry,” he said.


Judge Lynn Callahan called Rafferty’s case “heartbreaking” but said she did not accept that he had no way out of his situation.


“You embraced the evil, you studied it,” she said. She said Rafferty had been dealt “a lousy hand in life,” but she found nothing in the case that could be chalked up to the recklessness of youth.


“You could have been so much more; you are so intelligent,” the judge told Rafferty.


During the trial, jurors heard testimony that the teen helped dig graves for some of the men and was found in possession of guns and knives stolen from them after Beasley shot them.


Beasley’s trial is scheduled in the same courtroom for January 7. He faces the death penalty if convicted. Both Rafferty’s and Beasley’s attorneys are under a gag order and are not permitted to talk to the media.


Under Ohio law, juveniles older than 15 who are charged with a serious offense and crimes that involve a firearm are sent to adult court for trial.


Last summer, a U.S. Supreme Court decision struck down mandatory life sentences for juveniles. The high court found that judges and juries passing sentence on juvenile murders must weigh mitigating circumstances, including the youth’s role and family background.


A 2005 Supreme Court decision made it unconstitutional to execute anyone under the age of 18.


Rafferty’s attorney Jill Flagg objected to his sentence and will appeal.


In other incidents involving Craigslist and other social media, people advertising goods for sale or responding to ads have been attacked and killed.


In 2009, a former medical student was accused of killing a masseuse he met through Craigslist. In February, two men in Tennessee were accused of killing a man and a woman for “unfriending” the daughter of one of the suspects on Facebook.


(Reporting by Kim Palmer; Editing by Mary Wisniewski and Eric Walsh)


Internet News Headlines – Yahoo! News



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Philip Roth says he’s done writing
















NEW YORK (AP) — Exit, Philip Roth? Having conceived everything from turning into a breast to a polio epidemic in his native New Jersey, Roth has apparently given his imagination a rest.


The 79-year-old novelist recently told a French publication, Les inRocks, that his 2010 release “Nemesis” would be his last. Spokeswoman Lori Glazer of Houghton Mifflin Harcourt said Friday that she had spoken with Roth and that he confirmed his remarks. Roth’s literary agent, Andrew Wylie, declined comment.













Roth certainly produced, completing more than 20 novels over half a century and often turning out one a year. He won virtually every prize short of the Nobel and wrote such classics as “American Pastoral” and “Portnoy’s Complaint.”


His name will remain on new releases, if only because the Library of America has been issuing hardcover volumes of his work. Roth also is cooperating with award-winning biographer Blake Bailey on a book about his life.


The author chose an unexpected forum to break the news, but he has been hinting at his departure for years. He has said that he no longer reads fiction and seemed to say goodbye to his fictional alterego, Nathan Zuckerman, in the 2007 novel “Exit Ghost.”


Retirement is rarely the preferred option for writers, for whom the ability to tell stories or at least set down words is often synonymous with life itself. Poor health, discouragement and even madness are the more likely ways literary careers end. Roth apparently is fit and his recent novels had been received respectfully, if not with the awe of his most celebrated work.


“I don’t believe it,” Roth’s friend and fellow writer Cynthia Ozick said upon learning the news. “A writer who stops writing while still breathing has already declared herself posthumous.”


His parting words from “Nemesis”: “He seemed to us invincible.”


Roth’s interview appeared in French and has been translated, roughly, by The Associated Press. He tells Les inRocks that “Nemesis” was “mon dernier livre” (“My last book”) and refers to “Howard’s End” author E.M. Forster, and how he quit fiction in his 40s. Roth said he doesn’t plan to write a memoir, but will instead go through his archives and help ensure that Bailey’s biography comes out in his lifetime.


Explaining why he stopped, Roth said that at age 74 he became aware his time was limited and that he started re-reading his books of the past 20-30 years, in reverse order. He decided that he agreed with what the boxer Joe Louis had said late in life, that he had done the best he could with what he had.


Entertainment News Headlines – Yahoo! News



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Getting A Handle On Malaria in the Americas
















Malaria cases and deaths from the mosquito-borne disease have both declined substantially in the Americas, according to an update by the Pan American Health Organization (PAHO).


From 200 to 2011, cases dropped 59% and deaths declined 70%, PAHO reported Thursday  at its 6th Annual Malaria Day in the Americas Forum in Washingotn.













More than 541,000 confirmed malaria cases and 72 deaths from malaria were reported in 2011 in the region, PAHO says.


While the progress is impressive, it must continue, according to Dr. Socorro Gross, assistant director of PAHO.  ”We want to have zero cases and zero deaths,” she told those attending the forum.


RELATED: Fake Malaria Drugs Thwart Global Efforts to Treat Dangerous Diseases


Worldwide, malaria affects 250 million people each year, PAHO says. About 655,000 worldwide die of the disease annually.


The decline in the Americas (and elsewhere) is credited largely to the World Health Organization initiative known as T3.


The T3 initaitive includes testing, treating and tracking. Under it, officials in malaria-endemic countries are urged to move to universal access to both testing and treatment. They are encouraged to build stronger malaria surveillance systems.


Under T3, public health officials in countries with endemic malaria should test all suspected cases and treat confirmed cases with antimalarial drugs.


Each country is urged to have a surveillance system that will help them form policy and operations about malaria control.


At the forum, three countries were named this year’s Malaria Champions of the Americas: Brazil, Ecuador and Paraguay.


The countries were recognized for making significant strides against malaria.


Paraguay got the top honor. Its National Malaria Control Program was cited for reducing malaria burden by following the initiative.  As of 2011, the number of malaria cases reported there was down 99% compared to 2002. Paraguay last reported a malaria-related death in 1989.


The champions program was launched in 2008. It’s a joint effort of PAHO and WHO, the Pan American Health Education Foundation and the George Washington University Center for Global Health.


Despite the good news about declining cases and deaths in the Americas, officials at the forum repeatedly expressed the need for continued vigilance and control efforts.


In the Americas, more than 23 million people live in areas of malaria risk, says Dr. Don Tharpe, president of the Pan American Health Education Foundation.


It is easy to forget how malaria can ravage lives, he says. The elderly and infants are most vulnerable. The economic and educational fallout are both substantial.


Public health programs that include education, bed nets and other precautions as well as spraying can help reduce transmission, he says.


A parasite, Plasmodium, causes malaria, which is transmitted by the bites of mosquitoes infected by the parasite.


Malaria symptoms, which typically occur with in 10 to 15 days after the bite,  include headache, fever and vomiting.


RELATED: Cutting Rainforests Leads to More Malaria: Study


Untreated malaria can be life-threatening as it disrupts blood from getting to vital organs.


In many areas, the parasites have become resistant to many malaria medicines.


In the U.S., about 1,500 cases of malaria are diagnosed each year, according to the Centers for Disease Control and Prevention. Most of the cases area in  travelers returning from endemic areas.


The risk is greatest for travelers to sub-Saharan Africa, the CDC says. but the risk is present in any country with malaria.



Kathleen Doheny is a Los Angeles journalist who writes about health. She doesn’t believe inmiracle cures, but continues to hope someone will discover a way for joggers to maintain their pace.


Seniors/Aging News Headlines – Yahoo! News



Read More..

Getting A Handle On Malaria in the Americas
















Malaria cases and deaths from the mosquito-borne disease have both declined substantially in the Americas, according to an update by the Pan American Health Organization (PAHO).


From 200 to 2011, cases dropped 59% and deaths declined 70%, PAHO reported Thursday  at its 6th Annual Malaria Day in the Americas Forum in Washingotn.













More than 541,000 confirmed malaria cases and 72 deaths from malaria were reported in 2011 in the region, PAHO says.


While the progress is impressive, it must continue, according to Dr. Socorro Gross, assistant director of PAHO.  ”We want to have zero cases and zero deaths,” she told those attending the forum.


RELATED: Fake Malaria Drugs Thwart Global Efforts to Treat Dangerous Diseases


Worldwide, malaria affects 250 million people each year, PAHO says. About 655,000 worldwide die of the disease annually.


The decline in the Americas (and elsewhere) is credited largely to the World Health Organization initiative known as T3.


The T3 initaitive includes testing, treating and tracking. Under it, officials in malaria-endemic countries are urged to move to universal access to both testing and treatment. They are encouraged to build stronger malaria surveillance systems.


Under T3, public health officials in countries with endemic malaria should test all suspected cases and treat confirmed cases with antimalarial drugs.


Each country is urged to have a surveillance system that will help them form policy and operations about malaria control.


At the forum, three countries were named this year’s Malaria Champions of the Americas: Brazil, Ecuador and Paraguay.


The countries were recognized for making significant strides against malaria.


Paraguay got the top honor. Its National Malaria Control Program was cited for reducing malaria burden by following the initiative.  As of 2011, the number of malaria cases reported there was down 99% compared to 2002. Paraguay last reported a malaria-related death in 1989.


The champions program was launched in 2008. It’s a joint effort of PAHO and WHO, the Pan American Health Education Foundation and the George Washington University Center for Global Health.


Despite the good news about declining cases and deaths in the Americas, officials at the forum repeatedly expressed the need for continued vigilance and control efforts.


In the Americas, more than 23 million people live in areas of malaria risk, says Dr. Don Tharpe, president of the Pan American Health Education Foundation.


It is easy to forget how malaria can ravage lives, he says. The elderly and infants are most vulnerable. The economic and educational fallout are both substantial.


Public health programs that include education, bed nets and other precautions as well as spraying can help reduce transmission, he says.


A parasite, Plasmodium, causes malaria, which is transmitted by the bites of mosquitoes infected by the parasite.


Malaria symptoms, which typically occur with in 10 to 15 days after the bite,  include headache, fever and vomiting.


RELATED: Cutting Rainforests Leads to More Malaria: Study


Untreated malaria can be life-threatening as it disrupts blood from getting to vital organs.


In many areas, the parasites have become resistant to many malaria medicines.


In the U.S., about 1,500 cases of malaria are diagnosed each year, according to the Centers for Disease Control and Prevention. Most of the cases area in  travelers returning from endemic areas.


The risk is greatest for travelers to sub-Saharan Africa, the CDC says. but the risk is present in any country with malaria.



Kathleen Doheny is a Los Angeles journalist who writes about health. She doesn’t believe inmiracle cures, but continues to hope someone will discover a way for joggers to maintain their pace.


Seniors/Aging News Headlines – Yahoo! News



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Lockheed boss resigns over affair

















US defence company Lockheed Martin says its incoming president and chief executive officer has resigned over a relationship with a subordinate.













Christopher Kubasik resigned after an internal ethics investigation confirmed the “close personal relationship”, the company said in a statement.


He was due to take over as head of the company next year after serving as its chief operating officer.


Another Lockheed executive, Marillyn Hewson, will now become CEO in January.


Chairman and outgoing CEO Robert Stevens said he was “deeply disappointed and saddened” by the relationship, which he described as “inconsistent with our values and standards”.


But he said the company had a “strong leadership team and a robust succession plan”.


Lockheed Martin is a defence and aerospace company based in Maryland that employs some 120,000 worldwide.


Its net sales for 2011 were $ 46.5bn (£29bn).


BBC News – Business



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Syria opposition bloc elects Christian as leader
















DOHA, Qatar (AP) — Syria‘s main opposition group in exile has elected a Christian Paris-based former geography teacher as its new president.


George Sabra said Friday that his election as head of the Syrian National Council is a sign that the opposition is not plagued by sectarian divisions.













Sabra says the SNC‘s main demand is to receive weapons from the international community. The U.S. and some other foreign backers of rebels fighting the regime of President Bashar Assad have so far refused to send weapons for fear they can fall into the wrong hands.


Middle East News Headlines – Yahoo! News



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Spotify to raise $100 million at $3 billion valuation – report
















(Reuters) – Spotify is in the middle of a $ 100 million financing round that could value the music streaming company at just over $ 3 billion, the Wall Street Journal reported citing sources.


The Journal said Spotify would raise the fresh capital from multiple investors including Goldman Sachs. The WSJ report did not name any other investors.













Spotify has raised capital from outside investors several times since it set up shop in 2006, and was earlier reported to have been looking to secure a capital boost of about $ 200 million, at a valuation of about $ 4 billion.


Kleiner Perkins Caufield & Byers, Accel Partners and others have invested about $ 189 million in the company in its prior financing rounds.


The company has over 15 million active users and 4 million paying subscribers, for its on-demand service, which offers unlimited music streaming of some 18 million tracks.


(Reporting by Himank Sharma in Bangalore)


Internet News Headlines – Yahoo! News



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VP Joe Biden guest stars as celebrity crush on “Parks and Rec”
















LOS ANGELES (Reuters) – Someone has a big crush on U.S. Vice President Joe Biden – and now she is getting to meet him.


Biden will make his TV acting debut with a cameo on NBC‘s comedy “Parks and Recreation” as the celebrity crush of actress Amy Poehler‘s ditzy local councilwoman Leslie Knope, NBC said on Thursday.













Biden, 69, will play himself in the episode “Leslie vs. April,” airing November 15, where Knope, a city councilwoman for the fictional small town of Pawnee, Indiana, has a surprise meeting with the vice president in Washington D.C.


Knope has long described her ideal man as having the “brains of George Clooney and the body of Joe Biden.”


“Meeting Vice President Biden was a thrill for me and for Leslie,” Poehler said in a statement.


“He was a good sport and a great improviser. The vice president maintained his composure while I harassed him and invaded his personal space. The nation of ‘Parks and Rec’ will be forever grateful,” she added.


The scenes with Biden were shot in July in the chambers of the vice president’s ceremonial office, during the TV show’s recent trip to the nation’s capital to film scenes for this season’s storylines.


The biggest challenge of landing Biden’s cameo was keeping it a secret before Tuesday’s U.S. elections. Airing the episode prior to November 6 could have been equivalent to a campaign contribution to advertise a candidate, executive producer Michael Schur told Entertainment Weekly.


“Parks and Recreation” follows the Pawnee Parks department and its tireless deputy Knope, who puts all her efforts into improving her little hometown.


This is a big season for Poehler’s character, who is finally elected into city government, gets engaged to campaign advisor Ben Wyatt and meets her political heroes including Senators Barbara Boxer, Olympia Snow and John McCain, who were featured in September’s season premiere.


(Reporting By Piya Sinha-Roy, editing by Jill Serjeant)


TV News Headlines – Yahoo! News



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Calif. city plans to provide transgender surgeries
















SAN FRANCISCO (AP) — San Francisco is preparing to become the first U.S. city to provide and cover the cost of sex reassignment surgeries for uninsured transgender residents.


The city’s Health Commission voted Tuesday to create a comprehensive program for treating transgender people experiencing mental distress because of the mismatch between their bodies and their gender identities. San Francisco already provides transgender residents with hormones, counseling and routine health services, but has stopped short of offering surgical interventions, Public Health Director Barbara Garcia said Thursday after the vote was announced.













The idea for a new program that included surgeries came out of conversations between public health officials and transgender rights advocates who wanted mastectomies, genital reconstructions and other surgeries that are recommended for some transgender people covered under San Francisco’s 5-year-old universal health care plan.


At the urging of the San Francisco Board of Supervisors and the San Francisco-based Transgender Law Center, the commission agreed this week to drop sex reassignment surgery from the list of procedures specifically excluded from the Healthy San Francisco plan.


But Garcia described the move as “a symbolic process” for now because the city currently does not have the expertise, capacity or protocols in place to provide the surgeries through its clinics and public hospital.


“The community felt the exclusion on Healthy San Francisco was discriminatory and we wanted to change that as the first step,” she said.


Instead of expanding the existing plan, the Health Commission approved the establishment of a separate program that covers all aspects of transgender health, including gender transition. Garcia hopes to have it running by late next year, but said her department first needs to study how many people it would serve, how much it would cost, who would perform the surgeries and where they would be performed.


“Sex reassignment surgery is not the end all. It’s one service that some transgender people want and some don’t,” she said. “We can probably manage this over the next three years without much of a budget increase because we already have these (other) services covered.”


San Francisco in 2001 became the first city in the country to cover sex reassignment surgeries for government employees. Last year, Portland, Ore. did the same. The number of major U.S. companies covering the cost of gender reassignment surgery for transgender workers also doubled last year, reflecting a decades-long push by transgender activists to get insurance companies to treat such surgeries as medically necessary instead of elective procedures.


Kathryn Steuerman, a member of a transgender health advocacy group in San Francisco, said the city’s latest move would help residents avoid going into debt to finance operations related to gender transition, as she did.


“I am filled with hope and gratitude that we are achieving this level of support for the well-being of the transgender community,” Steuerman said.


Health News Headlines – Yahoo! News



Read More..

Calif. city plans to provide transgender surgeries
















SAN FRANCISCO (AP) — San Francisco is preparing to become the first U.S. city to provide and cover the cost of sex reassignment surgeries for uninsured transgender residents.


The city’s Health Commission voted Tuesday to create a comprehensive program for treating transgender people experiencing mental distress because of the mismatch between their bodies and their gender identities. San Francisco already provides transgender residents with hormones, counseling and routine health services, but has stopped short of offering surgical interventions, Public Health Director Barbara Garcia said Thursday after the vote was announced.













The idea for a new program that included surgeries came out of conversations between public health officials and transgender rights advocates who wanted mastectomies, genital reconstructions and other surgeries that are recommended for some transgender people covered under San Francisco’s 5-year-old universal health care plan.


At the urging of the San Francisco Board of Supervisors and the San Francisco-based Transgender Law Center, the commission agreed this week to drop sex reassignment surgery from the list of procedures specifically excluded from the Healthy San Francisco plan.


But Garcia described the move as “a symbolic process” for now because the city currently does not have the expertise, capacity or protocols in place to provide the surgeries through its clinics and public hospital.


“The community felt the exclusion on Healthy San Francisco was discriminatory and we wanted to change that as the first step,” she said.


Instead of expanding the existing plan, the Health Commission approved the establishment of a separate program that covers all aspects of transgender health, including gender transition. Garcia hopes to have it running by late next year, but said her department first needs to study how many people it would serve, how much it would cost, who would perform the surgeries and where they would be performed.


“Sex reassignment surgery is not the end all. It’s one service that some transgender people want and some don’t,” she said. “We can probably manage this over the next three years without much of a budget increase because we already have these (other) services covered.”


San Francisco in 2001 became the first city in the country to cover sex reassignment surgeries for government employees. Last year, Portland, Ore. did the same. The number of major U.S. companies covering the cost of gender reassignment surgery for transgender workers also doubled last year, reflecting a decades-long push by transgender activists to get insurance companies to treat such surgeries as medically necessary instead of elective procedures.


Kathryn Steuerman, a member of a transgender health advocacy group in San Francisco, said the city’s latest move would help residents avoid going into debt to finance operations related to gender transition, as she did.


“I am filled with hope and gratitude that we are achieving this level of support for the well-being of the transgender community,” Steuerman said.


Health News Headlines – Yahoo! News



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Asian stocks sink on US fiscal cliff fears
















HONG KONG (AP) — Asian stock markets sank Friday, weighed down by fears over the so-called U.S. “fiscal cliff” that investors see as a big threat to the economic recovery.


Japan‘s Nikkei 225 index fell 0.9 percent to 8,757.39 and Hong Kong‘s Hang Seng shed 0.5 percent to 21,453.49. South Korea‘s Kospi retreated 1 percent to 1,894.85 and Australia‘s S&P ASX 200 dropped 0.5 percent to 4,462.20.













The slump in Asia mirrored the trend in markets worldwide as investors have refocused on challenges to the world economy following U.S. President Barack Obama’s re-election. Many worry that gridlock in Washington will prevent the president and Congress from reaching a deal before the package of tax increases and government spending cuts kicks in on Jan. 1.


Declines were more muted in mainland China, where investors were awaiting a number of economic indicators that would provide the latest update on the slowdown in the world’s second biggest economy.


The Shanghai Composite Index dipped 0.3 percent to 2,065.92, while the Shenzhen Composite Index lost 0.3 percent to 828.78.


The Chinese benchmarks briefly swung into positive territory after a report released just after trading started showed October inflation had eased to 1.7 percent, giving room for more stimulus. But investors stayed cautious as they awaited industrial production, fixed asset investment and retail sales figures later in the day.


“Markets may stabilize and possibly rebound on Chinese data for October, which we expect to show acceleration of output amid muted price pressures,” strategists at Credit Agricole CIB wrote in a research note.


On Wall Street, the Dow closed down nearly 1 percent to 12,811.32, bringing its two-day loss to 434 points. The Standard and Poor’s 500 index fell 1.2 percent to 1,377.51 and the tech-heavy Nasdaq composite slipped 1.4 percent to 2,895.58.


In currencies, the euro weakened to $ 1.2748 from to $ 1.2750 late Thursday. The dollar strengthened to 79.49 Japanese yen from 79.38 yen.


Crude oil for December delivery was up 12 cents to $ 85.22 in electronic trading on the New York Mercantile Exchange. The contract rose 65 cents to close at $ 85.09 on Thursday.


Economy News Headlines – Yahoo! News



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Myanmar says Obama to visit later this month
















YANGON, Myanmar (AP) — President Barack Obama will make a groundbreaking visit later this month to Myanmar, an official said Thursday, following through with his policy of rapprochement to encourage democracy in the Southeast Asian nation.


The Myanmar official speaking from the capital, Naypyitaw, said Thursday that security for a visit on Nov. 18 or 19 had been prepared, but the schedule was not final. He asked not to be named because he was not authorized to give information to the media.













The official said Obama would meet with opposition leader Aung San Suu Kyi as well as government officials including reformist President Thein Sein.


It would be the first-ever visit to Myanmar by an American president. U.S. officials have not yet announced any plans for a visit, which would come less than two weeks after Obama’s election to a second term.


Obama’s administration has sought to encourage the recent democratic progress under Thein Sein by easing sanctions applied against Myanmar’s previous military regime.


Officials in nearby Thailand and Cambodia have already informally announced plans for visits by Obama that same week. Cambodia is hosting a summit meeting of the Association of Southeast Asian Nations, and Thailand is a longtime close U.S. ally.


The visit to Myanmar, also known as Burma, would be the culmination of a dramatic turnaround in relations with Washington as the country has shifted from five decades of ruinous military rule and shaken off the pariah status it had earned through its bloody suppression of democracy.


Obama’s ending of the long-standing U.S. isolation of Myanmar’s generals has played a part in coaxing them into political reforms that have unfolded with surprising speed in the past year. The U.S. has appointed a full ambassador and suspended sanctions to reward Myanmar for political prisoner releases and the election of Nobel laureate Suu Kyi to parliament.


From Myanmar’s point of view, the lifting of sanctions is essential for boosting a lagging economy that was hurt not only by sanctions that curbed exports and foreign investment, but also by what had been a protectionist, centralized approach. Thein Sein’s government has initiated major economic reforms in addition to political ones.


A procession of senior diplomats and world leaders have traveled to Myanmar, stopping both in the remote, opulent capital city, which was built by the former ruling junta, and at Suu Kyi’s dilapidated lakeside villa in the main city of Yangon, where she spent 15 years under house arrest. New Zealand announced Thursday that Prime Minister John Key would visit Myanmar after attending the regional meetings in Cambodia.


The most senior U.S. official to visit was Hillary Rodham Clinton, who last December became the first U.S. secretary of state to travel to Myanmar in 56 years.


The Obama administration regards the political changes in Myanmar as a marquee achievement in its foreign policy, and one that could dilute the influence of China in a country that has a strategic location between South and Southeast Asia, regions of growing economic importance.


But exiled Myanmar activists and human rights groups are likely to criticize an Obama visit as premature, rewarding Thein Sein before his political and economic reforms have truly taken root. The military — still dominant and implicated in rights abuses — has failed to prevent vicious outbreaks of communal violence in the west of the country that have left scores dead.


Asia News Headlines – Yahoo! News



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Dancing With The Stars Family Rallies On Twitter In Support Of Brooke Burke-Charvet Following Thyroid Cancer Diagnosis
















Members of the “Dancing with the Stars” family Tweeted their well-wishes for the show’s co-host, Brooke Burke-Charvet, who revealed on Thursday she has thyroid cancer.


Helio Castroneves, who was recently eliminated from the “All-Stars” season, said he is confident she will overcome the disease.













PLAY IT NOW: Brooke Burke-Charvet’s Sexy Lingerie Shoot!


“Hi @brookeburke, I have sure that you will win this battle. My affection for you,” the Indy driver wrote.


Brooke revealed on Thursday that she will be undergoing thyroid surgery and a thyroidectomy, and Erin Andrews, who competed in Season 10, noted she was praying for the host.


VIEW THE PHOTOS: The Lovely Brooke Burke-Charvet


“Thinking about @DancingABC friend @brookeburke..Prayers and all the best your way Brooke,” Erin wrote.


Also sending her kind words was Sabrina Bryan, who was eliminated last week on the show.


“@brookeburke hey girl!! You’re in my thoughts and prayers! Always here for you during this fight! Stay strong,” Sabrina wrote.


VIEW THE PHOTOS: Dancing With The Stars: All-Stars — Week 6


Season 13 vet Ricki Lake wrote, “@brookeburke sending huge healing love your way.”


Current contender Melissa Rycroft shared her support, Tweeting, “You’re such a strong woman, and I admire your courage. I hope you feel all the love and support behind you…We love you!”


VIEW THE PHOTOS: ‘Dancing’s’ Derek Hough


And some of the professional dancers chimed in too.


Pro Derek Hough (Brooke’s Season 7 partner) Tweeted, “Love you Brookie B. [You're] in my prayers.”


Cheryl Burke Tweeted, “I love u @brookeburke!! Stay strong. Will be praying for u and sending u lots of positive energy!”


– Jolie Lash


Copyright 2012 by NBC Universal, Inc. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


Social Media News Headlines – Yahoo! News



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Taylor Swift reigns over Billboard 200, Meek Mill debuts high
















LOS ANGELES (Reuters) – Country-pop star Taylor Swift held onto the top spot on the Billboard 200 album chart on Wednesday as her latest album “Red” kept rapper Meek Mill from the top spot.


“Red,” Swift’s fourth studio album safely took the No. 1 position after selling 344,000 copies according to figures from Nielsen SoundScan.













Last week, “Red” scored the highest first week U.S. sales in a decade after selling 1.2 million copies. The album has outsold One Direction’s “Up All Night” to become the second-biggest album of 2012, behind Adele’s juggernaut record “21,” which has sold more than 4 million copies this year.


Rapper Meek Mill entered the chart at No. 2 with his debut studio album “Dreams & Nightmares,” selling 164,000 copies. The rapper collaborated with fellow Maybach Music artists for his debut, including Trey Songz, Wale, Rick Ross and Mary J. Blige.


Ahead of the holiday season, two festive albums debuted on the chart, with veteran crooner Rod Stewart’s “Merry Christmas Baby” at No. 3 and Trans-Siberian Orchestra’s extended play record “Dreams of Fireflies (On a Christmas Night)” at No. 9.


Country singer Toby Keith landed at No. 6 with his latest album “Hope on the Rocks,” following his appearance and best music video win at the County Music Association (CMA) awards last week.


Country group Little Big Town also saw a boost from their CMA vocal group of the year win as their album “Tornado” climbed the chart to No. 10.


Canadian singer Neil Young and his band Crazy Horse scored their second top ten album this year with “Psychedelic Pill” at No. 8, following their “Americana” album in June.


Over on the Digital Songs chart, Korean rapper Psy held the top spot with his infectious dance-pop single “Gangnam Style,” while Bruno Mars’ “Locked Out of Heaven” remained at No. 2 and Ke$ ha’s “Die Young” was a non-mover at No. 3.


(Reporting by Piya Sinha-Roy, editing by Jill Serjeant)


Celebrity News Headlines – Yahoo! News



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Statins may be linked to cancer survival
















NEW YORK (Reuters Health) – Danish cancer patients taking cholesterol-lowering statin drugs were 15 percent less likely to die, of cancer or any other cause, than patients who were not on the popular medications, in a new study.


The pattern held regardless of a person’s age, cancer type, tumor size or whether it had spread. Only patients who had received chemotherapy showed no apparent benefit from taking statins – the most commonly-prescribed drugs in the world.













Eric Jacobs, a researcher at the American Cancer Society who was not involved in the new work, called the findings “intriguing and exciting” but said they “do not mean that people with cancer should start using statins in the hopes of improving their progress.”


The study, published Wednesday in the New England Journal of Medicine, did not look at whether the statins, with familiar brand names such as Lipitor and Mevacor, can prevent cancer – only at what happens once cancer is diagnosed.


Using multiple registries containing data on cancer, drug use, population characteristics and deaths for the nation of Denmark, the research team analyzed the cancer cases of 18,721 people over age 40 who were diagnosed between 1995 and 2007.


All were taking statins regularly before their cancer was discovered, and the study compared them to 277,204 people who had not regularly taken the drugs before getting cancer treatments.


Overall, the cancer death rate among statin users was 15 percent lower, and so was the rate of death from any cause.


The appearance of a benefit from taking statins was strongest for 13 cancer types in particular, ranging from an 11 percent lower death rate among pancreatic cancer patients to a 36 percent lower rate among cervical cancer patients. For 14 other tumor types, the results were less clear-cut.


The study’s senior author, Dr. Stig Bojesen of the University of Copenhagen compared the difference in mortality to that seen with chemotherapy. “The benefit of receiving chemotherapy versus not receiving chemotherapy is 15 percent to 20 percent, depending on cancer type,” he told Reuters Health. “What we see (in the new study) is comparable to that. That’s really something.”


The fact that a seeming benefit from statins was not seen in people taking chemotherapy, however, doesn’t mean that people should avoid chemotherapy treatment and turn to statins instead, Bojesen stressed.


Rather, he thinks therapeutic use of statins might be considered when no good chemotherapy option is available for a particular cancer type.


And, if his team’s finding is confirmed in a larger study, statins may offer an easy, inexpensive way to reduce cancer deaths in some patients, he added.


Because the drugs are available in generic form, “The daily cost is about 10 cents or something like that. It’s extremely cheap,” Bojesen said.


An estimated one in four Americans over age 45 takes statin drugs, which work in the liver to reduce the amount of “bad” cholesterol in the bloodstream.


Bojesen speculates that the drugs may be robbing cancer cells of an important building block of cell membranes, and thereby slowing tumor growth.


“Our hypothesis is that by reducing cholesterol, you steal cholesterol from the proliferating cancer cells … improving survival,” he said.


But there is cause for skepticism. The people who took less than the recommended dose of a statin had a higher rate of survival than cancer patients who took higher doses. A positive relationship between dose and response is usually seen as evidence, at least, of cause and effect.


“The absence of a dose trend might indicate that just some statin might be enough,” Bojesen said. “But this is just an observational study, so the exact dose and the exact mechanism is something we can’t clarify with this paper.”


In an editorial accompanying the new report, Dr. Neil Caporaso of the National Cancer Institute said the study is also limited because no information on factors such as smoking were available.


So, for instance, the higher likelihood that people taking statins had heart disease and might therefore have also been targeted for smoking cessation treatment, would muddy the connection between being on statins and having lower cancer mortality.


In addition, information on treatment with chemotherapy and radiation were missing for 72 percent of the people taking statins, he noted.


“Because this study was an observational study, the slightly lower cancer death rates among cancer patients who had used statins before their cancer diagnosis could have been caused by factors other than the statin itself,” Jacobs told Reuters Health. “People using statins may have been more likely to use aspirin, which has been linked with improved cancer survival in some recent studies.”


SOURCE: http://bit.ly/TuzoQN New England Journal of Medicine, online November 7, 2012.


Diseases/Conditions News Headlines – Yahoo! News



Read More..

Statins may be linked to cancer survival
















NEW YORK (Reuters Health) – Danish cancer patients taking cholesterol-lowering statin drugs were 15 percent less likely to die, of cancer or any other cause, than patients who were not on the popular medications, in a new study.


The pattern held regardless of a person’s age, cancer type, tumor size or whether it had spread. Only patients who had received chemotherapy showed no apparent benefit from taking statins – the most commonly-prescribed drugs in the world.













Eric Jacobs, a researcher at the American Cancer Society who was not involved in the new work, called the findings “intriguing and exciting” but said they “do not mean that people with cancer should start using statins in the hopes of improving their progress.”


The study, published Wednesday in the New England Journal of Medicine, did not look at whether the statins, with familiar brand names such as Lipitor and Mevacor, can prevent cancer – only at what happens once cancer is diagnosed.


Using multiple registries containing data on cancer, drug use, population characteristics and deaths for the nation of Denmark, the research team analyzed the cancer cases of 18,721 people over age 40 who were diagnosed between 1995 and 2007.


All were taking statins regularly before their cancer was discovered, and the study compared them to 277,204 people who had not regularly taken the drugs before getting cancer treatments.


Overall, the cancer death rate among statin users was 15 percent lower, and so was the rate of death from any cause.


The appearance of a benefit from taking statins was strongest for 13 cancer types in particular, ranging from an 11 percent lower death rate among pancreatic cancer patients to a 36 percent lower rate among cervical cancer patients. For 14 other tumor types, the results were less clear-cut.


The study’s senior author, Dr. Stig Bojesen of the University of Copenhagen compared the difference in mortality to that seen with chemotherapy. “The benefit of receiving chemotherapy versus not receiving chemotherapy is 15 percent to 20 percent, depending on cancer type,” he told Reuters Health. “What we see (in the new study) is comparable to that. That’s really something.”


The fact that a seeming benefit from statins was not seen in people taking chemotherapy, however, doesn’t mean that people should avoid chemotherapy treatment and turn to statins instead, Bojesen stressed.


Rather, he thinks therapeutic use of statins might be considered when no good chemotherapy option is available for a particular cancer type.


And, if his team’s finding is confirmed in a larger study, statins may offer an easy, inexpensive way to reduce cancer deaths in some patients, he added.


Because the drugs are available in generic form, “The daily cost is about 10 cents or something like that. It’s extremely cheap,” Bojesen said.


An estimated one in four Americans over age 45 takes statin drugs, which work in the liver to reduce the amount of “bad” cholesterol in the bloodstream.


Bojesen speculates that the drugs may be robbing cancer cells of an important building block of cell membranes, and thereby slowing tumor growth.


“Our hypothesis is that by reducing cholesterol, you steal cholesterol from the proliferating cancer cells … improving survival,” he said.


But there is cause for skepticism. The people who took less than the recommended dose of a statin had a higher rate of survival than cancer patients who took higher doses. A positive relationship between dose and response is usually seen as evidence, at least, of cause and effect.


“The absence of a dose trend might indicate that just some statin might be enough,” Bojesen said. “But this is just an observational study, so the exact dose and the exact mechanism is something we can’t clarify with this paper.”


In an editorial accompanying the new report, Dr. Neil Caporaso of the National Cancer Institute said the study is also limited because no information on factors such as smoking were available.


So, for instance, the higher likelihood that people taking statins had heart disease and might therefore have also been targeted for smoking cessation treatment, would muddy the connection between being on statins and having lower cancer mortality.


In addition, information on treatment with chemotherapy and radiation were missing for 72 percent of the people taking statins, he noted.


“Because this study was an observational study, the slightly lower cancer death rates among cancer patients who had used statins before their cancer diagnosis could have been caused by factors other than the statin itself,” Jacobs told Reuters Health. “People using statins may have been more likely to use aspirin, which has been linked with improved cancer survival in some recent studies.”


SOURCE: http://bit.ly/TuzoQN New England Journal of Medicine, online November 7, 2012.


Diseases/Conditions News Headlines – Yahoo! News



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China submarines soon to carry nukes, draft US report says
















WASHINGTON (Reuters) – China appears to be within two years of deploying submarine-launched nuclear weapons, adding a new leg to its nuclear arsenal that should lead to arms-reduction talks, a draft report by a congressionally mandated U.S. commission says.


China in the meantime remains “the most threatening” power in cyberspace and presents the largest challenge to U.S. supply chain integrity, the U.S.-China Economic and Security Review Commission said in a draft of its 2012 report to the U.S. Congress.













China is alone among the original nuclear weapons states to be expanding its nuclear forces, the report said. The others are the United States, Russia, Britain and France.


Beijing is “on the cusp of attaining a credible nuclear triad of land-based intercontinental ballistic missiles, submarine-launched ballistic missiles, and air-dropped nuclear bombs,” the report says.


China has had a largely symbolic ballistic missile submarine capability for decades but is only now set to establish a “near-continuous at-sea strategic deterrent,” the draft said.


The deployment of such a hard-to-track, submarine-launched leg of China’s nuclear arsenal could have significant consequences in East Asia and beyond. It also could add to tensions between the United States and China, the world’s two biggest economies.


Any Chinese effort to ensure a retaliatory capability against a notional U.S. nuclear strike “would necessarily affect Indian and Russian perceptions about the potency of their own deterrent capabilities vis-à-vis China,” the report said, for instance.


ARMS CONTROL TALKS URGED


China is party to many major international pacts and regimes regarding nuclear weapons and materials. But it remains outside of key arms limitation and control conventions, such as the New Strategic Arms Reduction Treaty signed in April 2010 and the 1987 Intermediate-Range Nuclear Forces Treaty. The United States historically has approached these bilaterally with Russia.


Congress should require the U.S. State Department to spell out current and planned efforts to integrate China into existing and future nuclear arms reduction, limitation, and control discussions and agreements, the draft said.


In addition, Congress should “treat with caution” any proposal to unilaterally, or in the context of a bilateral deal with Russia, reduce operational U.S. nuclear forces without clearer information being made available to the public about China’s nuclear stockpile and force posture, it said.


A spokesman for the Chinese embassy in Washington, Geng Shuang, did not immediately respond to a request for comment.


China is estimated by the Arms Control Association, a private nonpartisan group in Washington, to have a total of 240 nuclear warheads. The United States, by contrast, has some 5,113, including tactical, strategic and nondeployed weapons.


CHINA DEPLOYING NEW CLASS OF SUBS


Beijing already has deployed two of as many as five of a new class of nuclear-powered ballistic missile submarine. The JIN-class boat is due to carry the JL-2 submarine-launched ballistic missile with an estimated range of about 7,400 km (4,600 miles).


The new submarines and the JL-2 missile will give Chinese forces its “first credible sea-based nuclear capability,” the U.S. Defense Department said in its own 2012 annual report to Congress on military and security developments involving China.


The JL-2 program has faced repeated delays but may reach an initial operating capability within the next two years, according to the Pentagon report, released in May.


The Pentagon declined to comment directly on China’s march toward creating a credible nuclear “triad” involving strategic bombers, intercontinental ballistic missiles and submarine-launched ballistic missiles.


“We monitor carefully China’s military developments and urge China to exhibit greater transparency regarding its capabilities and intentions,” Lieutenant Colonel Monica Matoush, a Defense Department spokeswoman, said by email.


Any assessment of China’s ability to have a nuclear triad would be an intelligence matter and likely be classified in nature, she added.


The final version of the report is to be released next Wednesday by the U.S.-China commission, a 12-member bipartisan group set up in 2000 to report to U.S. lawmakers on security implications of U.S.-China trade.


The draft, in its section on cyber-related issues, called on the Congress to develop a sanctions regime to penalize specific companies found to engage in, or otherwise benefit from, industrial espionage.


Congress should define industrial espionage as an illegal subsidy subject to countervailing duties, it added.


Lawmakers also should craft legislation to boost the security of critical supply chains, “particularly in the context of U.S. government and military procurement,” the draft said.


(Editing by Lisa Shumaker)


Economy News Headlines – Yahoo! News



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Merkel says Germany, Britain must work together on EU
















LONDON (Reuters) – Germany and Britain must cooperate to work round their differences on the European Union‘s long-term spending plans, German Chancellor Angela Merkel said on Wednesday.


“Despite differences that we have it is very important for me that the UK and Germany work together,” Merkel said through a translator before a meeting in London with Prime Minister David Cameron to discuss the EU‘s 2014-2020 budget.













“We always have to do something that will stand up to public opinion back home. Not all of the expenditure that has been earmarked has been used with great efficiency … We need to address that,” she said.


EU leaders meet in Brussels on November 22-23 to try to secure a seven-year budget for the 27-nation bloc amid signs of differences of opinion over what action should be taken.


(Reporting by Peter Griffiths; Editing by Andrew Osborn)


Europe News Headlines – Yahoo! News



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Video game maker Activision scores big gains in 3Q
















SANTA MONICA, Calif. (AP) — Video game maker Activision Blizzard Inc. scored points in the third quarter with a performance that topped analysts’ forecasts.


The results announced Wednesday encouraged management to predict more good times in the crucial holiday shopping season when the company is counting on video game aficionados to snap up the latest edition in its popular “Call of Duty” franchise.













Activision credited “Diablo III,” a role-playing game designed for personal computers, and its latest version of “World of Warcraft” for moving its latest quarter to a higher level.


The company earned $ 226 million, or 20 cents per share, for the three months ending in September. That represented a 53 percent increase from net income of $ 148 million, or 13 cents per share a year ago.


Excluding items unrelated to its ongoing business, Activision made 15 cents per share. The company beat the average estimate of 8 cents per share among analysts surveyed by FactSet. Adjusted earnings included a gain of 4 cents per share from the resolution of a U.S. tax audit.


Revenue for the period increased 12 percent from last year to $ 841 million. That figure, though, includes sales of games with online components, a revenue stream that the company and analysts prefer to spread out over time.


With that adjustment, Activision’s third-quarter revenue would have risen by 20 percent to $ 751 million — about $ 41 million above analysts’ projections.


The third quarter ended with a flourish as Activision sold 2.7 million copies of “World of Warcraft: Mists of Pandaria” in the first week after its Sept. 25 release.


CEO Bobby Kotick believes Activision has another hit on its hand with “Call of Duty: Black Ops II,” scheduled to go on sale Tuesday.


“We feel good about our product line-up, in spite of a difficult and challenging macroeconomic environment that could worsen,” Kotick said in an interview Wednesday.


Activision, based in Santa Monica, Calif., doesn’t expect the weak economy to keep people from buying its games as gifts during the upcoming holidays.


In the fourth quarter the company expects adjusted earnings of 70 cents per share on adjusted revenue of $ 2.41 billion. Analysts, on average, expect adjusted earnings of 67 cents per share on adjusted revenue of $ 2.34 billion.


Activision shares rose 23 cents, or 2 percent, to $ 11.36 in after-hours trading following the release of its earnings report.


Gaming News Headlines – Yahoo! News



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Rihanna unveils Chris Brown duet “Nobodies Business”
















LOS ANGELES (Reuters) – R&B star Rihanna unveiled a duet entitled “Nobodies Business” with ex-boyfriend Chris Brown on Tuesday, three years after Brown was charged with assaulting her.


The song was part of an official track list that Barbadian singer Rihanna tweeted to her followers for her upcoming album “Unapologetic,” and comes after weeks of speculation in the media that the couple have rekindled their romance being spotted together at numerous events.













While Rihanna, 24, has stayed mum on her relationship status with Brown, the “Turn Up The Music” singer attended Rihanna‘s Halloween party last week and tweeted a photograph of himself dressed in Arab robes and a rifle.


Brown, 23, is currently halfway through his five-year probation after pleading guilty to assaulting Rihanna on the eve of the Grammy awards in 2009. He was ordered to complete community service and a domestic violence program.


Brown was given permission by a Los Angeles judge to embark on his European tour at a recent hearing overseeing his progress on his probation.


The former couple have had a tumultuous relationship in the last three years, including a restraining order against Brown following the assault.


But recently the two singers have made peace, coming together on a remix of Rihanna‘s raunchy song “Birthday Cake” earlier this year.


The Barbadian singer told Oprah Winfrey in an emotional interview in August that she and Brown now had a “very close friendship,” and that she still loved him.


Other collaborations on Rihanna‘s upcoming “Unapologetic” album include rapper Eminem, newcomer singer-songwriter Mikky Ekko and rapper Future.


(Reporting By Piya Sinha-Roy, editing by Jill Serjeant)


Celebrity News Headlines – Yahoo! News



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Novartis heart failure drug cuts death by 37 percent: study
















LOS ANGELES (Reuters) – An experimental Novartis AG drug to treat hospitalized acute heart failure patients reduced deaths by 37 percent compared with a placebo and appeared to be safe, according to data from a late stage clinical trial presented on Tuesday.


The drug, serelaxin, which is a form of a human hormone that relaxes blood vessels and eases stress on the heart and other organs, is considered one of the most important medicines in the Swiss drugmaker’s developmental pipeline.













“With a meaningful mortality benefit, we believe Serelaxin could represent a $ 2.5 billion (annual) sales opportunity,” Deutsche Bank analysts said in a research note prior to release of the final data at the American Heart Association scientific meeting in Los Angeles.


Novartis said it now planned to seek approval for serelaxin. In the study of 1,161 patients, the drug cut deaths from any cause at six months by 37 percent and led to a marked reduction in worsening of heart failure during hospitalization, researchers said.


Patients who received 48 hours of continuously infused serelaxin experienced more than 45 percent fewer episodes of worsening heart failure symptoms than those who got a placebo.


Novartis had previously disclosed that serelaxin met one of the study’s two primary goals measuring relief of dyspnea, or extreme shortness of breath – a common symptom of acute heart failure – and that it reduced deaths. But the company did not say by how much. By one measure, serelaxin led to a 19 percent improvement in dyspnea, researchers said.


The drug failed to hit a secondary goal of the study that combined cardiovascular death with need for reshospitalizations, but researchers felt the life saving benefit was more important.


“We did have a startling death benefit. One of the reasons there may have been an inability to show a decrease in hospitalizations is more patients were alive to be rehospitalized,” said Dr John Teerlink, one of the trial’s co-lead researchers.


The data showed that only 29 acute heart failure patients would have to be treated with serelaxin to prevent one cardiovascular death, said Teerlink, a cardiologist and heart failure specialist at the San Francisco VA Medical Center.


Doctors say there is an enormous need for a treatment for acute heart failure, with few available options for the condition in which the heart is unable to pump enough blood.


“If it was approved we would not only use it, there would be a mandate to use it because we don’t have anything for acute decompensated heart failure,” said Dr. Milton Packer, a prominent cardiologist from the University of Texas Southwest Medical Center in Dallas, who was not involved in the study.


“If that mortality finding is real, boy are we going to get excited,” said Packer, who has been a member of FDA advisory panels for heart drugs.


There are more than one million hospitalizations in the United States each year for acute heart failure and another million in Europe. About half of all patients die within five years of diagnosis, often as a result of acute episodes that require urgent hospital care.


TREATMENT BENEFITS


The study showed the Novartis drug also reduced the duration of time spent in intensive care units by almost half a day and cut the length of hospital stay by almost a full day.


There was no difference in serious side effects between the two groups, but there was a significant increase in kidney impairment in the placebo group, as the Novartis drug appears to prevent worsening of kidney function, researchers said.


Despite missing some of the pre-set end points, or goals, of the study, Novartis said it is likely to seek approval of the drug based on the trial results.


“We believe this is a strong set of data and have started discussions with the main regulatory agencies. Our filing strategy will be determined by the outcome of these discussions,” said Ameet Nathwani, Novartis’ global business franchise head for critical care.


Dr John McMurry of the University of Glasgow, who was on a panel to critique the study, said that if there were a second serelaxin trial that also showed a mortality benefit it would be hard for health regulators to ignore.


“I think the agent was beneficial. This drug is doing something good in terms of relief,” he said.


(Reporting by Bill Berkrot and Deena Beasley. Editing by Andre Grenon and Richard Pullin)


Medications/Drugs News Headlines – Yahoo! News



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